This study aimed at evaluating the relationship between organizational climate and organizational commitment among the workers in the National Health Insurance Scheme in the Bono East region. To achieve this aim, the research design with emphasis on survey research was adopted to achieve the stated objectives. The census technique was used to invite all the 70 staff of the authority to respond to likert scale questionnaire instrument. The data was analysed quantitatively with the aid of IBM-SPSS (both descriptive and inferential statistics) and the results presented by means of frequencies and percentages. The study revealed that the nature of climate in the organization reflect that of satisfaction with the comprehensive human resource practices such as job security, promotion, grievance structure. The study revealed the following factors influencing organizational climate including organizational context, structure, warmth and support, physical environment, individual autonomy, management and employee relationship structure as well as clear organizational values and norms. In terms of staff level of commitment to the organization, the findings showed that staff have high levels of both affective and continuance commitments. However, normative commitment is low among the staff of the authority. Organizational climate is found to be statistically significant in determining the organizational commitment of the employees. By way of recommendations, management of NHIA needs to keep pace with various components of the organizational climate within workplace environment, which improves their performance and increase the levels of affective and continuance commitments.